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CALSCALE:GREGORIAN
PRODID:UW-Madison-Physics-Events
BEGIN:VEVENT
SEQUENCE:0
UID:UW-Physics-Event-2519
DTSTART:20120224T213000Z
DURATION:PT1H0M0S
DTSTAMP:20260420T062446Z
LAST-MODIFIED:20120216T224014Z
LOCATION:2241 Chamberlin Hall (coffee at 4:30 pm)
SUMMARY:FT-IR spectrochemical imaging: Design and applications with Fo
 cal Plane Array and multiple beam synchrotron radiation source\, Physi
 cs Department Colloquium\, Carol Hirschmugl\, UW-Milwaukee
DESCRIPTION:* This work has been done with support from NSF (MRI-DMR-0
 619759 and CHE-1112433) and the Synchrotron Radiation Center\, which i
 s also supported by NSF (DMR-0537588) and UW-Milwaukee and UW-Madison.
 <br>
\n<br>
\nFT-IR spectrochemical imaging\, which combines the chemi
 cal specificity of mid-infrared spectroscopy with spatial specificity\
 , is an important demonstration of label-free molecular imaging. Mid-i
 nfrared optical frequencies are resonant with the vibrational frequenc
 ies of functional groups\, thus an absorption spectrum is a "molecular
  fingerprint" of the material at every pixel.  Each spectrum can be co
 rrelated with known material properties to extract chemical informatio
 n. Synchrotron based FT-IR spectrochemical imaging\, as recently imple
 mented at the Synchrotron Radiation Center in Stoughton\, WI\, demonst
 rates the new capability to achieve diffraction limited chemical imagi
 ng across the entire mid-infrared region\, simultaneously\, with high 
 signal to noise ratio.<br>
\n<br>
\nIRENI (Infrared Environmental Imag
 ing) extracts a large swath of radiation (320 hor. x 25 vert. mrads<su
 p>2</sup>) to homogeneously illuminate a commercial IR microscope equi
 pped with an infrared Focal Plane Array (FPA) detector. Wide field ima
 ges are collected. IRENI rapidly generates high quality\, high spatial
  resolution data.  The relevant advantages (spatial oversampling\, spe
 ed\, sensitivity and signal to noise ratio) will be presented and demo
 nstrated using examples from a variety of disciplines\, including form
 alin fixed and flash frozen tissue samples\, live cells\, fixed cells\
 , paint cross sections\, polymer fibers and novel nano-materials will 
 be presented.<br>
\n<br>
\nM.J. Nasse\, et al. "High resolution Fourie
 r-transform infrared chemical imaging with multiple synchrotron beams"
 \,  Nature Methods\, 8\, (2011) 413-416<br>
\n<br>
\nE.C. Mattson\, et
  al. "Evidence of Nanocrystalline Semiconducting Graphene Monoxide Dur
 ing Thermal Reduction of Graphene Oxide in Vacuum\,"  ACS Nano 5\, pp 
 9710-9717<br>
\n<br>
\nM.Z. Kastyak-Ibrahim\, et al. "Biochemical labe
 l-free tissue imaging with subcellular -resolution synchrotron FTIR wi
 th Focal Plane Array Detector\," NeuroImage 60\, (2012) 376-383.<br>
\
 n<br>
URL:https://www.physics.wisc.edu/events/?id=2519
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