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VERSION:2.0
CALSCALE:GREGORIAN
PRODID:UW-Madison-Physics-Events
BEGIN:VEVENT
SEQUENCE:0
UID:UW-Physics-Event-2812
DTSTART:20121002T170500Z
DURATION:PT1H0M0S
DTSTAMP:20260420T021625Z
LAST-MODIFIED:20120921T203545Z
LOCATION:4274 Chamberlin (refreshments will be served)
SUMMARY:Mitochondrial proteins\, pathways and pathogenesis\, Chaos & C
 omplex Systems Seminar\, Dave Pagliarini\, UW Department of Biochemist
 ry
DESCRIPTION:Mitochondria are ubiquitous\, tiny metabolic machines that
  live inside nearly all of our cells. Collectively\, the make up ~10% 
 of our body weight\, and consume ~90% of the oxygen that we breath. Th
 ey are best known for their role as "power plants" that transform diff
 erent fuel sources into the universal cellular energy currency\, ATP. 
 However\, their physiological functions are much more diverse\, and th
 eir dysfunction leads to a wide spectrum of human disorders ranging fr
 om cancer to neurodegeneration. My group studies the composition and b
 iogenesis of these organelles\, and how defects in specific mitochondr
 ial proteins gives rise to human disorders. To do so\, we leverage a b
 road range of techniques including mass spectrometry-based proteomics\
 , chemical genetics and mouse physiology.
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URL:https://www.physics.wisc.edu/events/?id=2812
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