Abstract: The Wisconsin Sloan Center for Systemic Change, or WiSC2, is a hub for innovating and leading transformative work for excellence in graduate education at UW. Supported by the Alfred P. Sloan Foundation, the aim of Systemic Change centers is to remove entrenched barriers to student success, improve student outcomes, and create educational environments that are more equitable and effective for all. Research at UW–Madison and elsewhere has shown that student success is influenced by students’ academic preparation and self-efficacy and their sense of community and their feelings of belonging. This is especially true for students from backgrounds historically excluded from higher education and from science.