Abstract: Even with only Standard Model interactions, neutrinos play a critical role in core-collapse supernovae, cooling the proto-neutron star, setting the conditions for nucleosynthesis, and likely powering the explosion. Their effects could be immensely more profound in the presence of new physics, often poorly constrained by laboratory experiments alone. In this talk, I will discuss the effects of the strong lepton number violating neutrino self-interactions (LNV νSI) on the infall phase of the core-collapse supernova evolution. Strong LNV νSI processes equilibrate all neutrino seas; hence, all neutrino species share a common temperature and chemical potential. The new lowered electron neutrino chemical potential renders increased electron captures. I will show how strong LNV vSI could alter the standard supernova collapse scenario. Unlike many existing studies focusing on the late evolution effects, this study simulated the impact of LNV vSI on the infall phase with a full analytic treatment. The rapid neutrino-antineutrino equilibration leads to entropy generation and enhanced electron capture that may impact star evolution and the emitted neutrino signal. Timely DUNE neutrino detectors can also independently probe this new physics.