Abstract: The problem of unification of general relativity with quantum physics was first recognized by Einstein as a key open issue over a century ago. While there have been significant advances, we still do not have a definitive theory. I will begin by summarizing my perspectives on why the problem is still open, why we have several distinct approaches, and what the current status of leading programs is. I will then discuss how big bang is naturally tamed by quantum geometry effects in the very early universe, and how this singularity resolution creates a 2-way bridge between theory and observations. This fascinating and surprising interplay between gravity, geometry and the quantum will be presented at a general level, suitable for non-experts.